While I *think* the Windows Central article provides more info than the app's page on Steam, it talks mostly about 4k displays. The app itself is designed to work with lower rez displays too, and since issues about window size pop up every so often in the game GOTD comments, along with comments about whatever game looking bad on current or higher rez screens, thought some folks might be interested.
windowscentral[.]com/how-steam-app-lossless-scaling-makes-gaming-4k-displays-less-painful
store[.]steampowered[.]com/app/993090/Lossless_Scaling/