A while ago working with my VMs I uninstalled Microsoft Security Essentials & added the trial version of Kaspersky to see if it had or caused any problems with GOTD offers, their wrappers etc. -- at that time in Windows 7 it did not. Since then both Windows & Kaspersky have changed -- Windows has received updates from Microsoft, the trial version of Kaspersky IS available for download is now 16.0.0.614(a), & the VirtualBox Host software is now v. 5.0.4 - 102546. It was time for new tests; this time results were mixed...
Kaspersky IS [v. 16.0.0.614(a)] in Windows 10 64 bit had no effect at all on the Zoomplayer GOTD. Unfortunately the one casualty I suffered from a hard drive failure was my 32 bit Windows 10 VM, which was an Insider build that had been upgraded twice to newer Insider builds, & so probably won't be replaced until the next Insider ISO release. At any rate, I tested the Kaspersky IS trial, finding no problem with the Zoom Player GOTD on a fully up to date copy of the regular version of Windows 10 Home 64 bit, as well as on the Windows 10 Pro 64 bit Insider build 10532.
I also tested that same version of the Kaspersky IS trial on a Windows 7 32 bit VM, where it again had no effect on the GOTD. Unfortunately I can't say the same for my win7 64 bit VM, where the freshly installed & updated Kaspersky IS trial prevented the GOTD from running. That same Windows 7 64 VM had been upgraded to the Windows 10 64 bit Home VM, including the small bit of software installed, where the Kaspersky trial worked with the same GOTD. That meant the 10 VM had the same software & the same drivers [though in some cases newer driver versions], which might point to one of the Microsoft Windows updates Windows 7 64 bit has received since the last time I performed the same testing.
I downloaded the Windows 7 VM that Microsoft offers, finding that it was the 32 bit version, so of no use testing in this case IMHO -- I was hoping for a 64 bit version that might not have received the same chain of Windows updates. Windows 7 ISOs are available to download currently at microsoft.com/en-us/software-download/windows7 -- replace the "en-us" as needed. [Note that you'll need to have your win7 key handy.]
Using that ISO [which I assume would be the latest], one could install win7, install Kaspersky software, & test with a GOTD. If that worked, Windows updates could be applied, one or a few at a time, testing the GOTD after every update or small batch of updates. If at some point Kaspersky software prevents the GOTD from running properly, then it would be possible to isolate the update that caused the break, simply by uninstalling the update -- or one out of a batch -- & re-testing to confirm it worked.
Using the latest win7 ISO *may* cure the problem, even with all available updates installed, but if not, any updates that broke GOTD downloads with Kaspersky installed could be researched to see if they were really needed -- the problem an update was intended to fix might not be security related, or an update might have been replaced by a later version addressing the same issue & files, but still show up in Windows Update. A VM might be ideal for such testing, but personally I can't promise it's something I'd get to soon.
Besides being a bit of work I can't get to at the moment, If an update or updates was shown to cause problems, there's no telling if anyone effected would consider uninstalling it, just as there's no telling if a future Windows 7 or Kaspersky update would break it again. Long story short, I'm unsure that there is or would be any interest or reason.
On Windows 10 as a cure I'm currently agnostic, but lean towards skeptical. My concerns fall into 2 categories... One, simply put win10 still feels & acts like a beta. At the moment I have several win10 installs -- I've installed a regular 64 bit pro copy + 32 & 64 bit pro Insider builds [though only the 32 bit version is currently on my HDD], I've got win10 32 Home on my tablet [+ a copy of the Insider 32 bit Pro version backed up], & have 2 win10 VMs [as above, used to be 3]. Yesterday [update Tuesday] I did not have the same experience with any of those copies of win10 -- that should not be. With Windows 7 the same updates were offered for 5 win7 installs [3 regular + 2 VMs, 32 & 64 bit, HP & Ult. versions], but between Windows & Store updates, no two copies of 10 were exactly the same, i.e. had the same updates offered.
The 2nd area of concern is the upgrade to 10 process itself -- I'm pretty confident that several million upgrades to 10 are [sometimes far] less than optimal installs. If a PC, laptop, or tablet had an OEM &/or OEM Windows recovery partition(s), those are likely still there, & could be worse than useless if/when activated. Drivers are usually migrated, but not always, not always to the correct ones, not always to the current versions, & if that wasn't enough, there are plenty of re-badged win7/8.1 drivers that simply don't work properly in 10. And you've still got the inherent weakness of the Windows in-place upgrade, that's been there at least since Vista -- the upgrade process tries to migrate all of the registry entries & critical files, inserting compatibility settings, & the result has never been perfect. Microsoft isn't recommending fresh installs for only one reason -- they've chosen not to let you use your valid, existing key, so the only way to get a free upgrade activated is to go through the upgrade process. Then you're supposed to wipe the disk & install fresh, as Microsoft hints.
That means saving all of your current driver setup packages, researching & downloading newer versions when available, performing an in-place upgrade to 10, getting rid of the partitions related to the copy of Windows you upgraded plus Windows 10 [there could be up to 6, or more if e.g. your backup software added any], installing & updating 10, making sure the correct drivers are installed, then installing your software. It's not that difficult but it is tedious, & most people can't/won't be bothered. Not installing fresh has [if eventually] caused issues in the past -- as 10 makes a few fundamental changes in how Windows works, I've no reason not to expect similar & worse.